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A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels

Wnt signaling regulates primary body axis formation across the Metazoa, with high Wnt signaling specifying posterior identity. Whether a common Wnt-driven transcriptional program accomplishes this broad role is poorly understood. We identified genes acutely affected after Wnt signaling inhibition in...

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Detalles Bibliográficos
Autores principales: Tewari, Aneesha G., Owen, Jared H., Petersen, Christian P., Wagner, Daniel E., Reddien, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821139/
https://www.ncbi.nlm.nih.gov/pubmed/31626630
http://dx.doi.org/10.1371/journal.pgen.1008401