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The hRPC62 subunit of human RNA polymerase III displays helicase activity

In Eukaryotes, tRNAs, 5S RNA and U6 RNA are transcribed by RNA polymerase (Pol) III. Human Pol III is composed of 17 subunits. Three specific Pol III subunits form a stable ternary subcomplex (RPC62-RPC39-RPC32α/β) being involved in pre-initiation complex formation. No paralogues for subunits of thi...

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Detalles Bibliográficos
Autores principales: Ayoubi, Leyla El, Dumay-Odelot, Hélène, Chernev, Aleksandar, Boissier, Fanny, Minvielle-Sébastia, Lionel, Urlaub, Henning, Fribourg, Sébastien, Teichmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821166/
https://www.ncbi.nlm.nih.gov/pubmed/31529052
http://dx.doi.org/10.1093/nar/gkz788