Cargando…

The hRPC62 subunit of human RNA polymerase III displays helicase activity

In Eukaryotes, tRNAs, 5S RNA and U6 RNA are transcribed by RNA polymerase (Pol) III. Human Pol III is composed of 17 subunits. Three specific Pol III subunits form a stable ternary subcomplex (RPC62-RPC39-RPC32α/β) being involved in pre-initiation complex formation. No paralogues for subunits of thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ayoubi, Leyla El, Dumay-Odelot, Hélène, Chernev, Aleksandar, Boissier, Fanny, Minvielle-Sébastia, Lionel, Urlaub, Henning, Fribourg, Sébastien, Teichmann, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821166/ https://www.ncbi.nlm.nih.gov/pubmed/31529052 http://dx.doi.org/10.1093/nar/gkz788

Ejemplares similares

Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry
por: Christian, Henning, et al.
Publicado: (2014)

A new role for FBP21 as regulator of Brr2 helicase activity
por: Henning, Lisa M., et al.
Publicado: (2017)

Active and passive mechanisms of helicases
por: Manosas, Maria, et al.
Publicado: (2010)

The putative RNase P motif in the DEAD box helicase Hera is dispensable for efficient interaction with RNA and helicase activity
por: Linden, Martin H., et al.
Publicado: (2008)

A conformational change in the helicase core is necessary but not sufficient for RNA unwinding by the DEAD box helicase YxiN
por: Karow, Anne R., et al.
Publicado: (2009)

Structure-function analysis of the RNA helicase maleless
por: Izzo, Annalisa, et al.
Publicado: (2008)

Pif1 is a force-regulated helicase
por: Li, Jing-Hua, et al.
Publicado: (2016)

Allosteric regulation of helicase core activities of the DEAD-box helicase YxiN by RNA binding to its RNA recognition motif
por: Samatanga, Brighton, et al.
Publicado: (2017)

‘Modulation of the enzymatic activities of replicative helicase (DnaB) by interaction with Hp0897: a possible mechanism for helicase loading in Helicobacter pylori’
por: Verma, Vijay, et al.
Publicado: (2016)

Visualizing helicases unwinding DNA at the single molecule level
por: Fili, Natali, et al.
Publicado: (2010)

Characterization of an unusual bipolar helicase encoded by bacteriophage T5
por: Wong, Io Nam, et al.
Publicado: (2013)

Mechanism of DNA loading by the DNA repair helicase XPD
por: Constantinescu-Aruxandei, Diana, et al.
Publicado: (2016)

Regulation of Rep helicase unwinding by an auto-inhibitory subdomain
por: Makurath, Monika A, et al.
Publicado: (2019)

Point mutations in the Rpb9-homologous domain of Rpc11 that impair transcription termination by RNA polymerase III
por: Iben, James R., et al.
Publicado: (2011)

A biochemically active MCM-like helicase in Bacillus cereus
por: Samuels, Martin, et al.
Publicado: (2009)

Collaborative coupling between polymerase and helicase for leading-strand synthesis
por: Manosas, Maria, et al.
Publicado: (2012)

Archaeal MCM has separable processivity, substrate choice and helicase domains
por: Barry, Elizabeth R., et al.
Publicado: (2007)

Characterization of RNA helicase A as component of STAT6-dependent enhanceosome
por: Välineva, Tuuli, et al.
Publicado: (2006)

Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase
por: Wang, Qixin, et al.
Publicado: (2010)

Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing
por: Koh, Hye Ran, et al.
Publicado: (2014)

Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase
por: Wang, Shuang, et al.
Publicado: (2015)

Mcm10 coordinates the timely assembly and activation of the replication fork helicase
por: Perez-Arnaiz, Patricia, et al.
Publicado: (2016)

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase
por: Chen, Michael C., et al.
Publicado: (2015)

Insights into the product release mechanism of dengue virus NS3 helicase
por: Adler, Natalia S, et al.
Publicado: (2022)

Identification of RNA helicases with unwinding activity on angiogenin-processed tRNAs
por: Drino, Aleksej, et al.
Publicado: (2023)

The domain structure of Helicobacter pylori DnaB helicase: the N-terminal domain can be dispensable for helicase activity whereas the extreme C-terminal region is essential for its function
por: Nitharwal, Ram Gopal, et al.
Publicado: (2007)

Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae
por: Dhar, Alok, et al.
Publicado: (2008)

Evidence for a functional dimeric form of the PcrA helicase in DNA unwinding
por: Yang, Ye, et al.
Publicado: (2008)

MRE11 complex links RECQ5 helicase to sites of DNA damage
por: Zheng, Lu, et al.
Publicado: (2009)

Class-specific restrictions define primase interactions with DNA template and replicative helicase
por: Larson, Marilynn A., et al.
Publicado: (2010)

Deciphering the molecular basis for nucleotide selection by the West Nile virus RNA helicase
por: Despins, Simon, et al.
Publicado: (2010)

Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA
por: Galletto, Roberto, et al.
Publicado: (2013)

Ebola virus VP35 has novel NTPase and helicase-like activities
por: Shu, Ting, et al.
Publicado: (2019)

Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively
por: Burnham, Daniel R., et al.
Publicado: (2017)

DNA substrate recognition and processing by the full-length human UPF1 helicase
por: Dehghani-Tafti, Saba, et al.
Publicado: (2017)

Dynamic structural insights into the molecular mechanism of DNA unwinding by the bacteriophage T7 helicase
por: Ma, Jian-Bing, et al.
Publicado: (2020)

Ring-shaped replicative helicase encircles double-stranded DNA during unwinding
por: Joo, Sihwa, et al.
Publicado: (2019)

Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
por: Marx, Sinduja K, et al.
Publicado: (2023)

Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein
por: Sakakibara, Nozomi, et al.
Publicado: (2008)

Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase
por: Sowd, Gregory, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_lb10r6a4f1oqqi1ckj2u1jeet8