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FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA

Methyl-5-uridine (m5U) is one the most abundant non-canonical bases present in cellular RNA, and in yeast is found at position U54 of tRNAs where modification is catalysed by the methyltransferase Trm2. Although the mammalian enzymes that catalyse m5U formation are yet to be identified via experimen...

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Detalles Bibliográficos
Autores principales: Carter, Jean-Michel, Emmett, Warren, Mozos, Igor Rdl, Kotter, Annika, Helm, Mark, Ule, Jernej, Hussain, Shobbir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821191/
https://www.ncbi.nlm.nih.gov/pubmed/31361898
http://dx.doi.org/10.1093/nar/gkz658