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FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA
Methyl-5-uridine (m5U) is one the most abundant non-canonical bases present in cellular RNA, and in yeast is found at position U54 of tRNAs where modification is catalysed by the methyltransferase Trm2. Although the mammalian enzymes that catalyse m5U formation are yet to be identified via experimen...
Autores principales: | Carter, Jean-Michel, Emmett, Warren, Mozos, Igor Rdl, Kotter, Annika, Helm, Mark, Ule, Jernej, Hussain, Shobbir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821191/ https://www.ncbi.nlm.nih.gov/pubmed/31361898 http://dx.doi.org/10.1093/nar/gkz658 |
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