Signatures of cell death and proliferation in perturbation transcriptomics data—from confounding factor to effective prediction

Transcriptional perturbation signatures are valuable data sources for functional genomics. Linking perturbation signatures to screenings opens the possibility to model cellular phenotypes from expression data and to identify efficacious drugs. We linked perturbation transcriptomics data from the LIN...

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Detalles Bibliográficos
Autores principales: Szalai, Bence, Subramanian, Vigneshwari, Holland, Christian H, Alföldi, Róbert, Puskás, László G, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821211/
https://www.ncbi.nlm.nih.gov/pubmed/31552418
http://dx.doi.org/10.1093/nar/gkz805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821211/
https://www.ncbi.nlm.nih.gov/pubmed/31552418
http://dx.doi.org/10.1093/nar/gkz805

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