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Diagnostic Accuracy of Early Secretory Antigenic Target-6–Free Interferon-gamma Release Assay Compared to QuantiFERON-TB Gold In-tube

BACKGROUND: Early secretory antigenic target-6 (ESAT-6) is an immunodominant Mycobacterium tuberculosis (M.tb) antigen included in novel vaccines against tuberculosis (TB) and in interferon-gamma (IFN-γ) release assays (IGRAs). Therefore, the availability of an ESAT-6–free IGRA is essential to deter...

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Detalles Bibliográficos
Autores principales: Nemes, Elisa, Abrahams, Deborah, Scriba, Thomas J, Ratangee, Frances, Keyser, Alana, Makhethe, Lebohang, Erasmus, Mzwandile, Mabwe, Simbarashe, Bilek, Nicole, Rozot, Virginie, Geldenhuys, Hennie, Hatherill, Mark, Lempicki, Maria D, Holm, Line Lindebo, Bogardus, Leah, Ginsberg, Ann M, Blauenfeldt, Thomas, Smith, Bronwyn, Ellis, Ruth D, Loxton, Andre G, Walzl, Gerhard, Andersen, Peter, Ruhwald, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821223/
https://www.ncbi.nlm.nih.gov/pubmed/30668657
http://dx.doi.org/10.1093/cid/ciz034