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MicroRNA-24 promotes pancreatic beta cells toward dedifferentiation to avoid endoplasmic reticulum stress-induced apoptosis

Current research indicates that beta cell loss in type 2 diabetes may be attributed to beta cell dedifferentiation rather than apoptosis; however, the mechanisms by which this occurs remain poorly understood. Our previous study demonstrated that elevation of microRNA-24 (miR-24) in a diabetic settin...

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Detalles Bibliográficos
Autores principales: Zhu, Yunxia, Sun, Yi, Zhou, Yuncai, Zhang, Yan, Zhang, Tao, Li, Yating, You, Weiyan, Chang, Xiaoai, Yuan, Li, Han, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821228/
https://www.ncbi.nlm.nih.gov/pubmed/30753517
http://dx.doi.org/10.1093/jmcb/mjz004