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Conserved HORMA domain-containing protein Hop1 stabilizes interaction between proteins of meiotic DNA break hotspots and chromosome axis

HORMA domain-containing proteins such as Hop1 play crucial regulatory roles in various chromosomal functions. Here, we investigated roles of the fission yeast Hop1 in the formation of recombination-initiating meiotic DNA double strand breaks (DSBs). Meiotic DSB formation in fission yeast relies on m...

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Detalles Bibliográficos
Autores principales: Kariyazono, Ryo, Oda, Arisa, Yamada, Takatomi, Ohta, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821256/
https://www.ncbi.nlm.nih.gov/pubmed/31665745
http://dx.doi.org/10.1093/nar/gkz754