Cargando…

Conserved HORMA domain-containing protein Hop1 stabilizes interaction between proteins of meiotic DNA break hotspots and chromosome axis

HORMA domain-containing proteins such as Hop1 play crucial regulatory roles in various chromosomal functions. Here, we investigated roles of the fission yeast Hop1 in the formation of recombination-initiating meiotic DNA double strand breaks (DSBs). Meiotic DSB formation in fission yeast relies on m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kariyazono, Ryo, Oda, Arisa, Yamada, Takatomi, Ohta, Kunihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821256/ https://www.ncbi.nlm.nih.gov/pubmed/31665745 http://dx.doi.org/10.1093/nar/gkz754

Ejemplares similares

Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2
por: West, Alan M V, et al.
Publicado: (2018)

Redirecting meiotic DNA break hotspot determinant proteins alters localized spatial control of DNA break formation and repair
por: Hyppa, Randy W, et al.
Publicado: (2021)

State changes of the HORMA protein ASY1 are mediated by an interplay between its closure motif and PCH2
por: Yang, Chao, et al.
Publicado: (2020)

The dual role of HOP2 in mammalian meiotic homologous recombination
por: Pezza, Roberto J., et al.
Publicado: (2014)

Mechanistic insights into the role of Hop2–Mnd1 in meiotic homologous DNA pairing
por: Zhao, Weixing, et al.
Publicado: (2014)

A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation
por: Tian, Miao, et al.
Publicado: (2018)

The Pch2 AAA+ ATPase promotes phosphorylation of the Hop1 meiotic checkpoint adaptor in response to synaptonemal complex defects
por: Herruzo, Esther, et al.
Publicado: (2016)

Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice
por: Dereli, Ihsan, et al.
Publicado: (2021)

Conservation and divergence of meiotic DNA double strand break forming mechanisms in Arabidopsis thaliana
por: Vrielynck, Nathalie, et al.
Publicado: (2021)

Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand break repair
por: Ma, Lijuan, et al.
Publicado: (2015)

A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks
por: Hatkevich, Talia, et al.
Publicado: (2021)

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination
por: Guan, Yongjuan, et al.
Publicado: (2022)

The synaptonemal complex central region modulates crossover pathways and feedback control of meiotic double-strand break formation
por: Lee, Min-Su, et al.
Publicado: (2021)

The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination
por: Guo, Rui, et al.
Publicado: (2020)

RPA resolves conflicting activities of accessory proteins during reconstitution of Dmc1-mediated meiotic recombination
por: Chan, Yuen-Ling, et al.
Publicado: (2019)

Meiotic prophase roles of Rec8 in crossover recombination and chromosome structure
por: Yoon, Sang-Wook, et al.
Publicado: (2016)

Two pathways drive meiotic chromosome axis assembly in Saccharomyces cerevisiae
por: Heldrich, Jonna, et al.
Publicado: (2022)

FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers
por: Girard, Chloe, et al.
Publicado: (2014)

Different functions for the domains of the Arabidopsis thaliana RMI1 protein in DNA cross-link repair, somatic and meiotic recombination
por: Bonnet, Simone, et al.
Publicado: (2013)

A moonlighting metabolic protein influences repair at DNA double-stranded breaks
por: Torres-Machorro, Ana Lilia, et al.
Publicado: (2015)

A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp
por: Altieri, Amanda S., et al.
Publicado: (2016)

Replication stress induces accumulation of FANCD2 at central region of large fragile genes
por: Okamoto, Yusuke, et al.
Publicado: (2018)

ESA1 regulates meiotic chromosome axis and crossover frequency via acetylating histone H4
por: Wang, Ying, et al.
Publicado: (2021)

DNA intermediates of meiotic recombination in synchronous S. pombe at optimal temperature
por: Hyppa, Randy W., et al.
Publicado: (2014)

Negative supercoils regulate meiotic crossover patterns in budding yeast
por: Tan, Taicong, et al.
Publicado: (2022)

Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair
por: Shahi, Ankita, et al.
Publicado: (2011)

Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance
por: Li, Shuyi, et al.
Publicado: (2009)

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks
por: Krietsch, Jana, et al.
Publicado: (2012)

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
por: Gavish-Izakson, Michal, et al.
Publicado: (2018)

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks
por: Britton, Sébastien, et al.
Publicado: (2020)

Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF
por: Jayaram, Sumithra, et al.
Publicado: (2008)

Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways
por: Wang, Minli, et al.
Publicado: (2013)

The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1
por: Colombo, Chiara Vittoria, et al.
Publicado: (2017)

A failure of meiotic chromosome segregation in a fbh1Δ mutant correlates with persistent Rad51-DNA associations
por: Sun, Weili, et al.
Publicado: (2011)

High-resolution characterization of CPD hotspot formation in human fibroblasts
por: Zavala, Anamaria G., et al.
Publicado: (2014)

MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis
por: Shang, Yongliang, et al.
Publicado: (2020)

Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates
por: Altmannova, Veronika, et al.
Publicado: (2023)

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
por: Jakob, Burkhard, et al.
Publicado: (2011)

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein
por: Yuan, Ying, et al.
Publicado: (2015)

RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella
por: Charlot, Florence, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_js3dj7f5eb8r56m6qr1u99kf1s