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Spacer acquisition from RNA mediated by a natural reverse transcriptase-Cas1 fusion protein associated with a type III-D CRISPR–Cas system in Vibrio vulnificus

The association of reverse transcriptases (RTs) with CRISPR–Cas system has recently attracted interest because the RT activity appears to facilitate the RT-dependent acquisition of spacers from RNA molecules. However, our understanding of this spacer acquisition process remains limited. We character...

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Detalles Bibliográficos
Autores principales: González-Delgado, Alejandro, Mestre, Mario Rodríguez, Martínez-Abarca, Francisco, Toro, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821258/
https://www.ncbi.nlm.nih.gov/pubmed/31504832
http://dx.doi.org/10.1093/nar/gkz746