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A transient reporter for editing enrichment (TREE) in human cells

Current approaches to identify cell populations that have been modified with deaminase base editing technologies are inefficient and rely on downstream sequencing techniques. In this study, we utilized a blue fluorescent protein (BFP) that converts to green fluorescent protein (GFP) upon a C-to-T su...

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Detalles Bibliográficos
Autores principales: Standage-Beier, Kylie, Tekel, Stefan J, Brookhouser, Nicholas, Schwarz, Grace, Nguyen, Toan, Wang, Xiao, Brafman, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821290/
https://www.ncbi.nlm.nih.gov/pubmed/31428784
http://dx.doi.org/10.1093/nar/gkz713