Fail-safe genetic codes designed to intrinsically contain engineered organisms

One challenge in engineering organisms is taking responsibility for their behavior over many generations. Spontaneous mutations arising before or during use can impact heterologous genetic functions, disrupt system integration, or change organism phenotype. Here, we propose restructuring the genetic...

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Detalles Bibliográficos
Autores principales: Calles, Jonathan, Justice, Isaac, Brinkley, Detravious, Garcia, Alexa, Endy, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821295/
https://www.ncbi.nlm.nih.gov/pubmed/31511890
http://dx.doi.org/10.1093/nar/gkz745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821295/
https://www.ncbi.nlm.nih.gov/pubmed/31511890
http://dx.doi.org/10.1093/nar/gkz745

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