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PathFXweb: a web application for identifying drug safety and efficacy phenotypes

SUMMARY: Limited efficacy and intolerable safety limit therapeutic development and identification of potential liabilities earlier in development could significantly improve this process. Computational approaches which aggregate data from multiple sources and consider the drug’s pathways effects cou...

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Detalles Bibliográficos
Autores principales: Wilson, Jennifer L, Wong, Mike, Chalke, Ajinkya, Stepanov, Nicholas, Petkovic, Dragutin, Altman, Russ B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821302/
https://www.ncbi.nlm.nih.gov/pubmed/31114840
http://dx.doi.org/10.1093/bioinformatics/btz419