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METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis

Post-transcriptional RNA modifications, the epitranscriptome, play important roles in modulating the functions of RNA species. Modifications of rRNA are key for ribosome production and function. Identification and characterization of enzymes involved in epitranscriptome shaping is instrumental for t...

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Detalles Bibliográficos
Autores principales: Haute, Lindsey Van, Hendrick, Alan G, D’Souza, Aaron R, Powell, Christopher A, Rebelo-Guiomar, Pedro, Harbour, Michael E, Ding, Shujing, Fearnley, Ian M, Andrews, Byron, Minczuk, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821322/
https://www.ncbi.nlm.nih.gov/pubmed/31665743
http://dx.doi.org/10.1093/nar/gkz735