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METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis
Post-transcriptional RNA modifications, the epitranscriptome, play important roles in modulating the functions of RNA species. Modifications of rRNA are key for ribosome production and function. Identification and characterization of enzymes involved in epitranscriptome shaping is instrumental for t...
Autores principales: | Haute, Lindsey Van, Hendrick, Alan G, D’Souza, Aaron R, Powell, Christopher A, Rebelo-Guiomar, Pedro, Harbour, Michael E, Ding, Shujing, Fearnley, Ian M, Andrews, Byron, Minczuk, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821322/ https://www.ncbi.nlm.nih.gov/pubmed/31665743 http://dx.doi.org/10.1093/nar/gkz735 |
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