Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability

Chromosomally-encoded toxin-antitoxin complexes are ubiquitous in bacteria and regulate growth through the release of the toxin component typically in a stress-dependent manner. Type II ribosome-dependent toxins adopt a RelE-family RNase fold and inhibit translation by degrading mRNAs while bound to...

Descripción completa

Detalles Bibliográficos
Autores principales: Pavelich, Ian J, Maehigashi, Tatsuya, Hoffer, Eric D, Ruangprasert, Ajchareeya, Miles, Stacey J, Dunham, Christine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821326/
https://www.ncbi.nlm.nih.gov/pubmed/31501867
http://dx.doi.org/10.1093/nar/gkz760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821326/
https://www.ncbi.nlm.nih.gov/pubmed/31501867
http://dx.doi.org/10.1093/nar/gkz760

Ejemplares similares