Cargando…
Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability
Chromosomally-encoded toxin-antitoxin complexes are ubiquitous in bacteria and regulate growth through the release of the toxin component typically in a stress-dependent manner. Type II ribosome-dependent toxins adopt a RelE-family RNase fold and inhibit translation by degrading mRNAs while bound to...
Autores principales: | Pavelich, Ian J, Maehigashi, Tatsuya, Hoffer, Eric D, Ruangprasert, Ajchareeya, Miles, Stacey J, Dunham, Christine M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821326/ https://www.ncbi.nlm.nih.gov/pubmed/31501867 http://dx.doi.org/10.1093/nar/gkz760 |
Ejemplares similares
-
YoeB–ribosome structure: a canonical RNase that requires the ribosome for its specific activity
por: Feng, Shu, et al.
Publicado: (2013) -
Molecular basis of ribosome recognition and mRNA hydrolysis by the E. coli YafQ toxin
por: Maehigashi, Tatsuya, et al.
Publicado: (2015) -
YoeB toxin is activated during thermal stress
por: Janssen, Brian D, et al.
Publicado: (2015) -
A YoeB toxin cleaves both RNA and DNA
por: McGillick, Julia, et al.
Publicado: (2021) -
Distinct oligomeric structures of the YoeB–YefM complex provide insights into the conditional cooperativity of type II toxin–antitoxin system
por: Xue, Lu, et al.
Publicado: (2020)