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A Bayesian model integration for mutation calling through data partitioning

MOTIVATION: Detection of somatic mutations from tumor and matched normal sequencing data has become among the most important analysis methods in cancer research. Some existing mutation callers have focused on additional information, e.g. heterozygous single-nucleotide polymorphisms (SNPs) nearby mut...

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Detalles Bibliográficos
Autores principales: Moriyama, Takuya, Imoto, Seiya, Hayashi, Shuto, Shiraishi, Yuichi, Miyano, Satoru, Yamaguchi, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821361/
https://www.ncbi.nlm.nih.gov/pubmed/30924874
http://dx.doi.org/10.1093/bioinformatics/btz233