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Cell-type-specific analysis of alternative polyadenylation using single-cell transcriptomics data
Alternative polyadenylation (APA) is emerging as an important layer of gene regulation because the majority of mammalian protein-coding genes contain multiple polyadenylation (pA) sites in their 3′ UTR. By alteration of 3′ UTR length, APA can considerably affect post-transcriptional gene regulation....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821429/ https://www.ncbi.nlm.nih.gov/pubmed/31501864 http://dx.doi.org/10.1093/nar/gkz781 |