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Oligomer Model of PB1 Domain of p62/SQSTM1 Based on Crystal Structure of Homo-Dimer and Calculation of Helical Characteristics

Autophagy is an important process for protein recycling. Oligomerization of p62/SQSTM1 is an essential step in this process and is achieved in two steps. Phox and Bem1p (PB1) domains can oligomerize through both basic and acidic surfaces in each molecule. The ZZ-type zinc finger (ZZ) domain binds to...

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Detalles Bibliográficos
Autores principales: Lim, Dahwan, Lee, Hye Seon, Ku, Bonsu, Shin, Ho-Chul, Kim, Seung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821454/
https://www.ncbi.nlm.nih.gov/pubmed/31600867
http://dx.doi.org/10.14348/molcells.2019.0096