KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1

Neuroinflammation is an important contributor to the pathogenesis of neurodegenerative disorders including Parkinson’s disease (PD). We previously reported that our novel synthetic compound KMS99220 has a good pharmacokinetic profile, enters the brain, exerts neuroprotective effect, and inhibits NF-...

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Detalles Bibliográficos
Autores principales: Lee, Ji Ae, Kim, Dong Jin, Hwang, Onyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821456/
https://www.ncbi.nlm.nih.gov/pubmed/31656063
http://dx.doi.org/10.14348/molcells.2019.0129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821456/
https://www.ncbi.nlm.nih.gov/pubmed/31656063
http://dx.doi.org/10.14348/molcells.2019.0129

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