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More than efficacy revealed by single-cell analysis of antiviral therapeutics

Because many aspects of viral infection dynamics and inhibition are governed by stochastic processes, single-cell analysis should provide more information than approaches using population averaging. We have developed a microfluidic device composed of ~6000 wells, with each well containing a microstr...

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Detalles Bibliográficos
Autores principales: Liu, Wu, Caglar, Mehmet U., Mao, Zhangming, Woodman, Andrew, Arnold, Jamie J., Wilke, Claus O., Cameron, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821460/
https://www.ncbi.nlm.nih.gov/pubmed/31692968
http://dx.doi.org/10.1126/sciadv.aax4761