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Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

Macrophages drive atherosclerotic plaque progression and rupture; hence, attenuating their atherosclerosis-inducing properties holds promise for reducing coronary heart disease (CHD). Recent studies in mouse models have demonstrated that Tribbles 1 (Trib1) regulates macrophage phenotype and shows th...

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Detalles Bibliográficos
Autores principales: Johnston, Jessica M., Angyal, Adrienn, Bauer, Robert C., Hamby, Stephen, Suvarna, S. Kim, Baidžajevas, Kajus, Hegedus, Zoltan, Dear, T. Neil, Turner, Martin, Wilson, Heather L., Goodall, Alison H., Rader, Daniel J., Shoulders, Carol C., Francis, Sheila E., Kiss-Toth, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821468/
https://www.ncbi.nlm.nih.gov/pubmed/31692955
http://dx.doi.org/10.1126/sciadv.aax9183