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Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion
Macrophages drive atherosclerotic plaque progression and rupture; hence, attenuating their atherosclerosis-inducing properties holds promise for reducing coronary heart disease (CHD). Recent studies in mouse models have demonstrated that Tribbles 1 (Trib1) regulates macrophage phenotype and shows th...
Autores principales: | Johnston, Jessica M., Angyal, Adrienn, Bauer, Robert C., Hamby, Stephen, Suvarna, S. Kim, Baidžajevas, Kajus, Hegedus, Zoltan, Dear, T. Neil, Turner, Martin, Wilson, Heather L., Goodall, Alison H., Rader, Daniel J., Shoulders, Carol C., Francis, Sheila E., Kiss-Toth, Endre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821468/ https://www.ncbi.nlm.nih.gov/pubmed/31692955 http://dx.doi.org/10.1126/sciadv.aax9183 |
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