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Differences and similarities in the effects of ibrutinib and acalabrutinib on platelet functions

While efficient at treating B-cell malignancies, Bruton tyrosine kinase (BTK) inhibitors are consistently reported to increase the risk of bleeding. Analyzing platelet aggregation response to collagen in platelet-rich plasma allowed us to identify two groups in the healthy population characterized b...

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Detalles Bibliográficos
Autores principales: Series, Jennifer, Garcia, Cédric, Levade, Marie, Viaud, Julien, Sié, Pierre, Ysebaert, Loïc, Payrastre, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821604/
https://www.ncbi.nlm.nih.gov/pubmed/30819914
http://dx.doi.org/10.3324/haematol.2018.207183