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KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently involving genes implicated in the mitogen activated protein kinase (MAPK) pathway, as KRAS, NRAS, and, less frequently, BRAF. Because KRAS/NRAS/BR...

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Detalles Bibliográficos
Autores principales: Pasca, Sergiu, Tomuleasa, Ciprian, Teodorescu, Patric, Ghiaur, Gabriel, Dima, Delia, Moisoiu, Vlad, Berce, Cristian, Stefan, Cristina, Ciechanover, Aaron, Einsele, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821642/
https://www.ncbi.nlm.nih.gov/pubmed/31709194
http://dx.doi.org/10.3389/fonc.2019.01137