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Clinical Features and MicroRNA Expression Patterns Between AML Patients With DNMT3A R882 and Frameshift Mutations

Background: DNA methyltransferase 3A (DNMT3A) plays a unique role in hematopoiesis and acute myeloid leukemia (AML) pathogenesis. While the influences of DNMT3A mutation subtypes are still under debate. Purpose: Exploration of the clinical and molecular differences between AML patients carrying DNMT...

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Detalles Bibliográficos
Autores principales: Yang, Li, Shen, Ke'Feng, Zhang, Mei'Lan, Zhang, Wei, Cai, Hao'Dong, Lin, Li'Man, Long, Xiao'Lu, Xing, Shu'Gang, Tang, Yang, Xiong, Jie, Wang, Jia'Chen, Li, Deng'Ju, Zhou, Jian'Feng, Xiao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821681/
https://www.ncbi.nlm.nih.gov/pubmed/31709191
http://dx.doi.org/10.3389/fonc.2019.01133