Cargando…

Characterisation of proguanylin expressing cells in the intestine – evidence for constitutive luminal secretion

Guanylin, a peptide implicated in regulation of intestinal fluid secretion, is expressed in the mucosa, but the exact cellular origin remains controversial. In a new transgenic mouse model fluorescent reporter protein expression driven by the proguanylin promoter was observed throughout the small in...

Descripción completa

Detalles Bibliográficos
Autores principales: Dye, Florent Serge, Larraufie, Pierre, Kay, Richard, Darwish, Tamana, Rievaj, Juraj, Goldspink, Deborah A., Meek, Claire L., Middleton, Stephen J., Hardwick, Richard H., Roberts, Geoffrey P., Percival-Alwyn, Jennifer L., Vaughan, Tris, Ferraro, Franco, Challis, Benjamin G., O’Rahilly, Stephen, Groves, Maria, Gribble, Fiona M., Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821700/
https://www.ncbi.nlm.nih.gov/pubmed/31666564
http://dx.doi.org/10.1038/s41598-019-52049-0