Cargando…

Intracerebroventricular injection of ouabain causes mania-like behavior in mice through D2 receptor activation

Intracerebroventricular (ICV) administration of ouabain, an inhibitor of the Na, K-ATPase, is an approach used to study the physiological functions of the Na, K-ATPase and cardiotonic steroids in the central nervous system, known to cause mania-like hyperactivity in rats. We describe a mouse model o...

Descripción completa

Detalles Bibliográficos
Autores principales: Lopachev, Alexander, Volnova, Anna, Evdokimenko, Anna, Abaimov, Denis, Timoshina, Yulia, Kazanskaya, Rogneda, Lopacheva, Olga, Deal, Alex, Budygin, Evgeny, Fedorova, Tatiana, Gainetdinov, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821712/
https://www.ncbi.nlm.nih.gov/pubmed/31666560
http://dx.doi.org/10.1038/s41598-019-52058-z