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Intracerebroventricular injection of ouabain causes mania-like behavior in mice through D2 receptor activation
Intracerebroventricular (ICV) administration of ouabain, an inhibitor of the Na, K-ATPase, is an approach used to study the physiological functions of the Na, K-ATPase and cardiotonic steroids in the central nervous system, known to cause mania-like hyperactivity in rats. We describe a mouse model o...
Autores principales: | Lopachev, Alexander, Volnova, Anna, Evdokimenko, Anna, Abaimov, Denis, Timoshina, Yulia, Kazanskaya, Rogneda, Lopacheva, Olga, Deal, Alex, Budygin, Evgeny, Fedorova, Tatiana, Gainetdinov, Raul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821712/ https://www.ncbi.nlm.nih.gov/pubmed/31666560 http://dx.doi.org/10.1038/s41598-019-52058-z |
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