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Empagliflozin and Dulaglutide are Effective against Obesity-induced Airway Hyperresponsiveness and Fibrosis in A Murine Model

Patients with asthma with obesity experience severe symptoms, are unresponsive to conventional asthma treatment, and lack proper pharmacotherapy. Empagliflozin and dulaglutide, developed for diabetes, reduce weight, decrease insulin resistance, and exert additive effects. We evaluated the efficacy o...

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Detalles Bibliográficos
Autores principales: Park, Hye Jung, Han, Heejae, Oh, Eun-Yi, Kim, Sung Ryeol, Park, Kyung Hee, Lee, Jae-Hyun, Park, Jung-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821734/
https://www.ncbi.nlm.nih.gov/pubmed/31666643
http://dx.doi.org/10.1038/s41598-019-51648-1