8-OxoG in GC-rich Sp1 binding sites enhances gene transcription in adipose tissue of juvenile mice

The oxidation of guanine to 8-oxoguanine (8-oxoG) is the most common type of oxidative DNA lesion. There is a growing body of evidence indicating that 8-oxoG is not only pre-mutagenic, but also plays an essential role in modulating gene expression along with its cognate repair proteins. In this stud...

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Detalles Bibliográficos
Autores principales: Park, Jong Woo, Han, Young In, Kim, Sung Woo, Kim, Tae Min, Yeom, Su Cheong, Kang, Jaeku, Park, Joonghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821754/
https://www.ncbi.nlm.nih.gov/pubmed/31666587
http://dx.doi.org/10.1038/s41598-019-52139-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821754/
https://www.ncbi.nlm.nih.gov/pubmed/31666587
http://dx.doi.org/10.1038/s41598-019-52139-z

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