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8-OxoG in GC-rich Sp1 binding sites enhances gene transcription in adipose tissue of juvenile mice
The oxidation of guanine to 8-oxoguanine (8-oxoG) is the most common type of oxidative DNA lesion. There is a growing body of evidence indicating that 8-oxoG is not only pre-mutagenic, but also plays an essential role in modulating gene expression along with its cognate repair proteins. In this stud...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821754/ https://www.ncbi.nlm.nih.gov/pubmed/31666587 http://dx.doi.org/10.1038/s41598-019-52139-z |