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Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes

Notch signaling is involved in the early onset of osteoarthritis. The aim of this study was to investigate the role of Notch signaling changes during proliferation and differentiation of chondrocyte, and to testify the mechanism of MMP-13 regulation by Notch and Runx2 expression changes during osteo...

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Detalles Bibliográficos
Autores principales: Xiao, Di, Bi, Ruiye, Liu, Xianwen, Mei, Jie, Jiang, Nan, Zhu, Songsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821756/
https://www.ncbi.nlm.nih.gov/pubmed/31666602
http://dx.doi.org/10.1038/s41598-019-52125-5