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A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca(2+) channels
Ca(v)3 / T-type Ca(2+) channels are dynamically regulated by intracellular Ca(2+) ions, which inhibit Ca(v)3 availability. Here, we demonstrate that this inhibition becomes irreversible in the presence of non-hydrolysable ATP analogs, resulting in a strong hyperpolarizing shift in the steady-state i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821770/ https://www.ncbi.nlm.nih.gov/pubmed/31666636 http://dx.doi.org/10.1038/s41598-019-52194-6 |