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Clonal pattern dynamics in tumor: the concept of cancer stem cells
We present a multiphase model for solid tumor initiation and progression focusing on the properties of cancer stem cells (CSC). CSCs are a small and singular cell sub-population having outstanding capacities: high proliferation rate, self-renewal and extreme therapy resistance. Our model takes all t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821776/ https://www.ncbi.nlm.nih.gov/pubmed/31666555 http://dx.doi.org/10.1038/s41598-019-51575-1 |