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Clonal pattern dynamics in tumor: the concept of cancer stem cells

We present a multiphase model for solid tumor initiation and progression focusing on the properties of cancer stem cells (CSC). CSCs are a small and singular cell sub-population having outstanding capacities: high proliferation rate, self-renewal and extreme therapy resistance. Our model takes all t...

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Detalles Bibliográficos
Autores principales: Olmeda, Fabrizio, Ben Amar, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821776/
https://www.ncbi.nlm.nih.gov/pubmed/31666555
http://dx.doi.org/10.1038/s41598-019-51575-1