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Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells
Organoids derived from human pluripotent stem cells are interesting models to study mechanisms of morphogenesis and promising platforms for disease modeling and drug screening. However, they mostly remain incomplete as they lack stroma, tissue resident immune cells and in particular vasculature, whi...
Autores principales: | Wörsdörfer, Philipp, Dalda, Nahide, Kern, Anna, Krüger, Sarah, Wagner, Nicole, Kwok, Chee Keong, Henke, Erik, Ergün, Süleyman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821804/ https://www.ncbi.nlm.nih.gov/pubmed/31666641 http://dx.doi.org/10.1038/s41598-019-52204-7 |
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