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The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis

Akkermansia muciniphila utilises colonic mucin as its substrate. Abundance is reduced in ulcerative colitis (UC), as is the relative proportion of sulphated mucin in the mucus gel layer (MGL). It is unknown if these phenomena are related, however reduced sulphated mucins could contribute to reduced...

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Detalles Bibliográficos
Autores principales: Earley, Helen, Lennon, Grainne, Balfe, Áine, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821857/
https://www.ncbi.nlm.nih.gov/pubmed/31666581
http://dx.doi.org/10.1038/s41598-019-51878-3