Details of the cooperative binding of piperlongumine with rat serum albumin obtained by spectroscopic and computational analyses

Piperlongumine (PPL) has presented a variety of important pharmacological activities. In recent pharmacokinetics studies in rats, this molecule reached 76.39% of bioavailability. Although PPL is present in the bloodstream, no information is found on the interaction between PPL and rat serum albumin...

Descripción completa

Detalles Bibliográficos
Autores principales: Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, de Freitas Lima, Marcelo, Cornélio, Marinônio Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821919/
https://www.ncbi.nlm.nih.gov/pubmed/31666676
http://dx.doi.org/10.1038/s41598-019-52187-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821919/
https://www.ncbi.nlm.nih.gov/pubmed/31666676
http://dx.doi.org/10.1038/s41598-019-52187-5

Ejemplares similares