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Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells

BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide (PT) expresses multiple anti-cancer and a...

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Detalles Bibliográficos
Autores principales: Zhu, Shi Mao, Park, Yong Ran, Seo, Seung Yong, Kim, In Hee, Lee, Soo Teik, Kim, Sang Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821947/
https://www.ncbi.nlm.nih.gov/pubmed/31426622
http://dx.doi.org/10.5217/ir.2019.00031