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Enhanced blood-brain-barrier penetrability and tumor-targeting efficiency by peptide-functionalized poly(amidoamine) dendrimer for the therapy of gliomas

Glioblastoma is one of the most common primary tumor types of central nervous system (CNS) with high malignance and lethality. Although many treatment options are currently available, the therapy of brain cancers remains challenging because of blood-brain-barrier (BBB) which prevents most of the che...

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Detalles Bibliográficos
Autores principales: Liu, Changliang, Zhao, Zijian, Gao, Houqian, Rostami, Iman, You, Qing, Jia, Xinru, Wang, Chen, Zhu, Ling, Yang, Yanlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821994/
https://www.ncbi.nlm.nih.gov/pubmed/31687320
http://dx.doi.org/10.7150/ntno.38954