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Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma

Advanced colorectal carcinoma is currently incurable, and new therapies are urgently needed. We report that phosphotyrosine‐dependent Eph receptor signaling sustains colorectal carcinoma cell survival, thereby uncovering a survival pathway active in colorectal carcinoma cells. We find that genetic a...

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Detalles Bibliográficos
Autores principales: DiPrima, Michael, Wang, Dunrui, Tröster, Alix, Maric, Dragan, Terrades‐Garcia, Nekane, Ha, Taekyu, Kwak, Hyeongil, Sanchez‐Martin, David, Kudlinzki, Denis, Schwalbe, Harald, Tosato, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822245/
https://www.ncbi.nlm.nih.gov/pubmed/31545551
http://dx.doi.org/10.1002/1878-0261.12576