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Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma
Advanced colorectal carcinoma is currently incurable, and new therapies are urgently needed. We report that phosphotyrosine‐dependent Eph receptor signaling sustains colorectal carcinoma cell survival, thereby uncovering a survival pathway active in colorectal carcinoma cells. We find that genetic a...
Autores principales: | DiPrima, Michael, Wang, Dunrui, Tröster, Alix, Maric, Dragan, Terrades‐Garcia, Nekane, Ha, Taekyu, Kwak, Hyeongil, Sanchez‐Martin, David, Kudlinzki, Denis, Schwalbe, Harald, Tosato, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822245/ https://www.ncbi.nlm.nih.gov/pubmed/31545551 http://dx.doi.org/10.1002/1878-0261.12576 |
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