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Oncogenic Ras mutant causes the hyperactivation of NF‐κB via acceleration of its transcriptional activation
It is well established that nuclear factor κB (NF‐κB) acts as one of the most important transcription factors for tumor initiation and progression, as it both protects cells from apoptotic/necrotic signals and accelerates angiogenesis and tumor metastasis, which is mediated via the expression of tar...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822247/ https://www.ncbi.nlm.nih.gov/pubmed/31580526 http://dx.doi.org/10.1002/1878-0261.12580 |