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The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis
OBJECTIVE: Skeletal muscle insulin signaling is a major determinant of muscle growth and glucose homeostasis. Protein kinase B/Akt plays a prominent role in mediating many of the metabolic effects of insulin. Mice and humans harboring systemic loss-of-function mutations in Akt2, the most abundant Ak...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822261/ https://www.ncbi.nlm.nih.gov/pubmed/31444134 http://dx.doi.org/10.1016/j.molmet.2019.08.001 |