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The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis

OBJECTIVE: Skeletal muscle insulin signaling is a major determinant of muscle growth and glucose homeostasis. Protein kinase B/Akt plays a prominent role in mediating many of the metabolic effects of insulin. Mice and humans harboring systemic loss-of-function mutations in Akt2, the most abundant Ak...

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Detalles Bibliográficos
Autores principales: Jaiswal, N., Gavin, M.G., Quinn, W.J., Luongo, T.S., Gelfer, R.G., Baur, J.A., Titchenell, P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822261/
https://www.ncbi.nlm.nih.gov/pubmed/31444134
http://dx.doi.org/10.1016/j.molmet.2019.08.001