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pTuneos: prioritizing tumor neoantigens from next-generation sequencing data

BACKGROUND: Cancer neoantigens are expressed only in cancer cells and presented on the tumor cell surface in complex with major histocompatibility complex (MHC) class I proteins for recognition by cytotoxic T cells. Accurate and rapid identification of neoantigens play a pivotal role in cancer immun...

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Detalles Bibliográficos
Autores principales: Zhou, Chi, Wei, Zhiting, Zhang, Zhanbing, Zhang, Biyu, Zhu, Chenyu, Chen, Ke, Chuai, Guohui, Qu, Sheng, Xie, Lu, Gao, Yong, Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822339/
https://www.ncbi.nlm.nih.gov/pubmed/31666118
http://dx.doi.org/10.1186/s13073-019-0679-x