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MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

BACKGROUND: The involvement of non-neuronal cells and the cells of innate immunity has been attributed to the initiation and progression of ALS. TDP-43 pathology is observed in a broad spectrum of ALS cases and is one of the most commonly shared pathologies. The potential involvement of the neuroimm...

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Detalles Bibliográficos
Autores principales: Jara, Javier H., Gautam, Mukesh, Kocak, Nuran, Xie, Edward F., Mao, Qinwen, Bigio, Eileen H., Özdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822373/
https://www.ncbi.nlm.nih.gov/pubmed/31666087
http://dx.doi.org/10.1186/s12974-019-1589-y