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In silico selection of functionally important proteins from the mialome of Ornithodoros erraticus ticks and assessment of their protective efficacy as vaccine targets

BACKGROUND: New candidate protective antigens for tick vaccine development may be identified by selecting and testing antigen candidates that play key biological functions. After blood-feeding, tick midgut overexpresses proteins that play essential functions in tick survival and disease transmission...

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Detalles Bibliográficos
Autores principales: Pérez-Sánchez, Ricardo, Manzano-Román, Raúl, Obolo-Mvoulouga, Prosper, Oleaga, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822432/
https://www.ncbi.nlm.nih.gov/pubmed/31666116
http://dx.doi.org/10.1186/s13071-019-3768-1