Neuromedin B mediates IL-6 and COX-2 expression through NF-κB/P65 and AP-1/C-JUN activation in human primary myometrial cells

Neuromedin B (NMB) and its receptor regulate labor onset by mediating inflammatory factors; however the underlying mechanisms remain poorly understood. The present study is aimed to investigate the mechanisms of NMB-induced cyclo-oxygenase 2 (COX-2) expression and interleukin (IL)-6 generation in hu...

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Detalles Bibliográficos
Autores principales: Zhu, Texuan, Chen, Jingfei, Zhao, Yanhua, Zhang, Jiejie, Peng, Qiaozhen, Huang, Jingrui, Luo, Jiefeng, Zhang, Weishe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822491/
https://www.ncbi.nlm.nih.gov/pubmed/31527064
http://dx.doi.org/10.1042/BSR20192139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822491/
https://www.ncbi.nlm.nih.gov/pubmed/31527064
http://dx.doi.org/10.1042/BSR20192139

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